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《医学前沿(英文)》 2023年 第17卷 第1期 页码 93-104 doi: 10.1007/s11684-021-0892-z
关键词: chemotherapy cervical cancer lymph node metastasis concurrent chemoradiotherapy quality of life
Present status and progress of neoadjuvant chemoradiotherapy for esophageal cancer
null
《医学前沿(英文)》 2013年 第7卷 第2期 页码 172-179 doi: 10.1007/s11684-013-0268-0
Trimodality based on neoadjuvant chemoradiotherapy (nCRT) followed by surgery is gaining popularity as a treatment strategy for locally advanced esophageal cancer. In this review, we summarize the role of nCRT and the recommended nCRT regimens based on clinical trials and meta-analyses. We analyze the relationship of nCRT with pathologic complete response (pCR) and then identify potential predictive markers of response. Compared with surgery alone and neoadjuvant chemotherapy followed by surgery, trimodality provides longer survival and has the advantage of local control compared with definitive chemoradiotherapy. The standard regimen is a platinum-based regimen with a radiation dose range of 41.4–50.4βGy by conventional fractionation. Evidence shows that patients with pCR tend to live longer than non-responders, indicating that pCR is a significant prognostic factor for patients with esophageal cancer. Individualized medicine requires predictive markers of individual patients based on their own genes. Currently, no definite marker is proved to be sufficiently sensitive and specific for use in clinical practice, although 18-fluorodeoxyglucose positron emission tomography shows promise in predicting response to nCRT.
Long JIANG, Yang GUO, Shikui CHEN, Peng WEI, Na LEI, Xianfeng David GU
《机械工程前沿(英文)》 2019年 第14卷 第2期 页码 171-189 doi: 10.1007/s11465-019-0530-5
关键词: concurrent topology optimization parametric level set method cardinal basis function shell-infill structure design conformal mapping
Concurrent fatigue crack growth simulation using extended finite element method
Zizi LU, Yongming LIU,
《结构与土木工程前沿(英文)》 2010年 第4卷 第3期 页码 339-347 doi: 10.1007/s11709-010-0078-2
关键词: small time scale model extended finite element method (X-FEM) crack growth multiaxial
《环境科学与工程前沿(英文)》 2022年 第16卷 第5期 doi: 10.1007/s11783-021-1491-6
• A high-efficiency N-doped porous carbon adsorbent for Cr(VI) was synthesized.
关键词: Chromium(VI) Nitrogen-doped porous carbon Adsorption Reduction Loofah sponge
DDUC:数据更新与编码解耦的纠删码系统 Research Article
屠要峰1,2,肖蓉2,韩银俊1,2,陈正华2,金浩2,齐学成2,孙辛远2
《信息与电子工程前沿(英文)》 2023年 第24卷 第5期 页码 716-730 doi: 10.1631/FITEE.2200466
标题 作者 时间 类型 操作
Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage
期刊论文
Concurrent optimization of structural topology and infill properties with a CBF-based level set method
Long JIANG, Yang GUO, Shikui CHEN, Peng WEI, Na LEI, Xianfeng David GU
期刊论文
Concurrent fatigue crack growth simulation using extended finite element method
Zizi LU, Yongming LIU,
期刊论文
Concurrent adsorption and reduction of chromium(VI) to chromium(III) using nitrogen-doped porous carbon
期刊论文